Endocrine Abstracts

Angelman syndrome (AS) and Prader-Willi syndrome (PWS) are distinct neurogenetic disorders involving the imprinting mechanism at 15q11–13 region. We report on 4 years and 9 months old boy who was referred to our laboratory in order to investigate a clinical bilateral cryptorquidy. The patient was born to non-consanguineous and healthy biological parents. Informed consent for publication was obtained from the parents. After normal pregnancy, the patient was delivered by ca...

Introduction: Hypothyroidism is a rare cause of early puberty in childhood. It reduces the growth rate by decreasing the amplitude of GH pulses. We report the case of a child who developed precocious puberty and reduced speed consequent to hypothyroidism growth. The treatment of thyroid disease with levothyroxine led to regression of pubertal development and resumption of growth.Methods: A.J.S., female, 1 year and 5 months of age at first consultation. S...